How Cannabidiol Acts on the Body of Humans and Animals?

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By extracting cannabidiol from the cannabis plant you acquire an oily essence rich in various cannabinoids with varying concentrations (depending on the type of plant, form of extraction, storage and origin).

An oil containing cannabidiol as the main active substance is called CBD oil, which exists in various concentrations and for different purposes.

How Cannabidiol acts on the body of humans and animals

CBD OIL EFFECTS

The human body is capable of producing cannabinoids, called endocannabinoids. Several cannabinoids from the Cannabis Plant, including cannabidiol, are agonists. This means that these substances activate, in the presence of a receptor (protein or protein complex), the transmission of signals in certain cells.

Research has uncovered the Endocanabinoid system in the human body, leading to the conclusion that cannabidiol from the cannabis plant acts in the body as a hormone or neurotransmitter, although it is not a substance of the body itself that mimics or replaces the effect of a messenger.

Body receptors are influenced by cannabinoids. These receptors, called CB1-receptor and CB2-receptor are found throughout the body, more precisely in the nervous system, organs, glands, the digestive tract, skin, tissues and mostly the brain.

Research into the effects of cannabis on the human body found two types of receptors that are influenced by cannabinoids of pure CBD.

These so-called CB-1 and CB-2 receptors are spread throughout the body, more precisely in the brain (where the highest concentration is found), the nervous system, organs, glands, digestive tract, skin and tissues. While CB-1 type receptors (the phyto-cannabinoid THC for example is linked to it) are more associated with coordination, movements, sensation of pain, emotions, mood, thought, appetite and memories, the CB-2 type receptors influence our immune system, inflammations and pain.

Contrary to what was previously thought, new findings assume that cannabidiol does not act directly on the CB-2 receptor, but that this substance induces the body to use its own cannabinoids. The endogenous cannabinoid system includes these two receptors and is part of our nervous system.

This physiological system has been named after the cannabis plant and can be found in all mammals. The SEC in our body is now considered one of the most important physiological systems in terms of maintaining and achieving good health.


Regarding the ​Balance of the Body

Balance is fundamental to our body because only then do we feel healthy and happy. Only when we are in balance can we prosper. The responsible in our body for this inner stability is the endocanabinoid system with its cannabinoid receptors present in the brain, central and peripheral nervous system, in the organs, tissues, immune cells, glands, digestive tract and even in the skin. The maintenance of our state of balance is also called in homeostasis medicine.

SEC receptors have a wireless connection with the whole body and constantly try to regulate the body, promoting its stability, regardless of the influences and variations that it goes through. The endogenous cannabinoid system therefore collaborates with the body in a variety of internal physiological processes and helps to regulate them.

The four main tasks of the SEC are: neuroprotection (the attempt to prevent nerve cells from dying), stress regeneration, immune balance and homeostatic regulation.

It helps the body, among other things in what it corresponds:

  • ​memory capacity
  • ​motor control
  • ​immune function
  • ​to mood
  • ​bone development
  • ​reproduction
  • ​the perception of pain
  • ​appetite
  • ​to sleep

The Role of CBD Oil

Cannabidiol is one of the most important plant cannabinoids of the cannabis plant. Cannabidiol (et al.) Stimulates the cannabinoid receptors CB1 and CB2 in case of body imbalance. Endocannabinoids in the body thus receive active support from "exogenous" cannabis plant phyto-cannabinoids, especially cannabidiol, since these are very similar to cannabinoids in the body itself. CBD oil stimulates the body to regulate and balance itself again.

It affects the pH balance in the blood, the perception of pain, the regulation of appetite, mood, energy level, memory and, above all, the immune system. Therefore, it can be very beneficial to take cannabidiol oil in case of illness, inflammation, disturbances or pain in the body.

CBD Oil for Animals

As explained in detail above, cannabidiol affects the endogenous cannabinoid system in humans. However, once this discovered system is present in all mammals (humans are similar to animals), it naturally also works in animals without side effects. Most studies are also conducted on animals. You can also do something good for your pet (dog, cat, horse etc.).


Karly Millar

    Karly Millar

    A Doctor of Public Health, Karly Millar has accrued more than ten years of experience, making a name for herself as a researcher, writer, policy analyst, and project manager specializing in public health and international development. She earned her PhD in Community and Behavioural Health at the Colorado School of Public Health, her Master’s Degree in Global Health and Public Policy at the University of Edinburgh, and her Bachelor’s Degree with Honours in Biomedical Sciences (with minours in Biology and Psychology) at the University of Waterloo.