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Hemp and marijuana plant are both from the cannabis sativa plants. These plants contain two popular compounds, CBD and THC. CBD is mainly used for medicinal purposes, THC is normally used for recreational needs. However, sometimes these two compounds can be used to produce the entourage effect. Below is an overview of CBD and THC.

Comparative Overview of CBD and THC Based on Facts

1. Overview of Cannabinoid

A cannabinoid is a chemical compound that acts on cannabinoid receptors in animals. It is found naturally or it can also be manufactured. Naturally, it is found in the cannabis plant. There are approximately 483 known compounds found in cannabis plant. However, the two most notable cannabinoids found in the Cannabis are tetrahydrocannabinol (THC) and cannabidiol (CBD).

Research shows that cannabinoids have a great influence on the endocannabinoid system. This may lead to a great breakthrough in the field of medicine. Most consumers don’t know the difference between THC and CBD. This article, therefore, attempts to show the difference between the two.

2. Overview of THC

THC is a compound found in marijuana species of the cannabis plant. THC is psychoactive, this means it causes a “high” feeling. This compound is the reason why marijuana has “high” effect. As a result, people tend to abuse it for recreational purposes. In medicine, THC is less attractive because it’s psychoactive.

You can extract both CBD and THC from Marijuana. However, CBD from marijuana usually has some traces of THC. The best source of CBD extract comes from the Hemp plant. This is because hemp has less than 0.3% concentration of THC. On the other hand, you get a higher quality THC from marijuana.

3. Intoxicating Differences between CBD and THC

First, it is important to know that CBD and THC have a similar molecular structure. But despite the similarity, they do not have the same psycho effect. In fact, CBD is not psychoactive. THC intoxicates the user by binding with cannabinoid receptors. Note that cannabinoids are receptors found in the endocannabinoid system of the body and they are CB1 and CB2.

THC usually binds with CB1 and CB2 but it has a higher affinity to CB1. CB1 is primarily found in the brain. It’s worth noting that THC is also known to be CB1 agonist. This means it has the ability to activate CB1 receptor. On the other hand, CBD does not bind with either CB1 or CB2 receptors. In fact, research shows that CBD is CB1 antagonist.

The activation of CB1 by THC in the brain is what usually causes the “high” feeling. It’s the leading reason to why people abuse marijuana. CBD is not only a CB1 antagonist but it also inhibits THC from binding with CB1. As a result, CBD can help inhibit the effects of THC on the user.

4. High-CBD Cannabis Strains: What Are They?

Are you looking for effective CBD products for pain relief? If so, then you need high-strain products. Note that a farmer can crossbreed industrial Hemp and marijuana. The new strain will have higher levels of both THC and CBD ratios. This strain is what is referred to as High-CBD cannabis strain. It may provide CBD and THC in the following ratios:

High THC- Low CBD 

The new breed will have a higher THC concentration than CBD. For example, THC may range between 10%-30%while CBD is less than that.

Balanced CBD-THC 

This strain of plant has an equal range of CBD and THC compounds. It may contain between 5%-15% of THC and CBD compounds.

High CBD-Low THC

This cannabis strain has higher concentrations of CBD. For example, the plant can have between 5%-20% of CBD.THC is usually less than range i.e. less than 5%.

5. Popular Use Cases of CBD

CBD has been known to have therapeutic values. As a result, most people turn to CBD pain relief cream products. CBD topical products and edibles can help to significantly reduce pain. This is because the compound has anti-inflammatory properties. Therefore, it effectively helps to ease mild and chronic pain. 

Since CBD is nonpsychoactive, it can’t result in addiction. It is popular for patients suffering from different forms of pain and other conditions. CBD has become popular in providing relief to certain conditions. Below are some conditions that patients use CBD to manage them.

CBD for Cancer

Cancer is a medical condition that is characterized by the development of abnormal cells. This illness usually causes excruciating pain to its patients. Besides that, the involved treatment procedures normally cause painful experiences. However, products such as CBD edibles gummies can help to minimize all these effects. This is because CBD has anti-inflammatory and antiemetic properties. It’s, therefore, effective in pain-relieving and reducing the symptoms of nausea.

CBD for Arthritis 

Arthritis is a medical condition that causes joint inflammation. Patients also experience pain and stiffness on the joints. This disease has no cure and conventional drugs are only effective for pain management. However, research shows that CBD oils can relieve arthritis pain. CBD cream for pain can help to significantly alleviate arthritic pain. Just make sure that you buy the best CBD cream online.

CBD for Epilepsy and Seizures

Clinical evidence shows that CBD can treat epilepsy. This is because it eases the frequency of seizures associated with epilepsy. Besides that, it helps to reduce the severity of the seizures. Most patients using CBD products normally experienced great relief.

6. Are there any Harmful effects?

CBD has a good safety profile. This means that a lot of people can use it without experiencing side effects. However, there are certain instances where it can result in harmful side effects to the user. They include:

  • Drowsiness: The calming effect of CBD can also cause slight drowsiness. This is more pronounced when it is a higher dosage to relieve pain. However, it only takes a little time and you will feel better again.
  • Dry mouth: Studies show that CBD reduces the production of saliva. This is what normally leads to dryness of the mouth.
  • Lowering blood pressure. The use of CBD can cause a slight drop in blood pressure. This may lead to the feeling light-headedness for a moment.

7. Takeaway

Both CBD and THC have their benefits. However, THC is great for recreational purposes because it’s psychoactive. While these two compounds come from the same plant, they have different users. However, it’s still possible to use them together. The combination of CBD and THC usually leads to the entourage effect.


  • https://www.leafly.com/news/cannabis-101/whats-the-deal-with-these-high-cbd-strains
  • https://www.projectcbd.org/
  • https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd
  • https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=1&contentid=1925
(Last Updated On: December 4, 2019)

A Doctor of Public Health, Lacy Ryan has accrued more than ten years of experience, making a name for herself as a researcher, writer, policy analyst, and project manager specializing in public health and international development.She earned her PhD in Community and Behavioural Health at the Colorado School of Public Health, her Master’s Degree in Global Health and Public Policy at the University of Edinburgh, and her Bachelor’s Degree with Honours in Biomedical Sciences (with minours in Biology and Psychology) at the University of Waterloo.